2020-02-20 00:56:30 +01:00
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#lang racket
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;;; dds/networks
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;;; This module provides some quick definitions for and analysing
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;;; network models. A network is a set of variables which are updated
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;;; according to their corresponding update functions. The variables
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;;; to be updated at each step are given by the mode.
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;;;
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;;; This model can generalise Boolean networks, TBANs, multivalued
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;;; networks, etc.
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2020-05-28 00:24:17 +02:00
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(require "utils.rkt" "generic.rkt" "functions.rkt" graph racket/random)
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2020-02-20 00:56:30 +01:00
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(provide
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2020-02-23 11:10:18 +01:00
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;; Structures
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(struct-out dynamics)
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2020-07-23 00:11:14 +02:00
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(contract-out [struct tbf/state ([weights (hash/c variable? number?)]
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2020-07-23 00:02:35 +02:00
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[threshold number?])])
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2020-02-20 14:13:48 +01:00
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;; Functions
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2020-02-23 12:10:27 +01:00
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(contract-out [update (-> network? state? (set/c variable? #:kind 'dont-care) state?)]
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2020-02-20 00:56:30 +01:00
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[make-state (-> (listof (cons/c symbol? any/c)) state?)]
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2020-02-26 15:51:25 +01:00
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[make-state-booleanize (-> (listof (cons/c symbol? (or/c 0 1))) state?)]
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2020-02-26 20:47:38 +01:00
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[booleanize-state (-> state? state?)]
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2020-02-20 14:13:48 +01:00
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[make-network-from-functions (-> (listof (cons/c symbol? update-function/c)) network?)]
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[update-function-form->update-function (-> update-function-form? update-function/c)]
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2020-02-20 00:56:30 +01:00
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[network-form->network (-> network-form? network?)]
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[make-network-from-forms (-> (listof (cons/c symbol? update-function-form?))
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2020-02-20 15:17:32 +01:00
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network?)]
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2020-02-20 15:56:48 +01:00
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[list-interactions (-> network-form? variable? (listof variable?))]
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2020-02-22 22:27:40 +01:00
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[build-interaction-graph (-> network-form? graph?)]
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2020-02-23 09:12:01 +01:00
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[build-all-states (-> domain-mapping/c (listof state?))]
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2020-02-23 11:51:59 +01:00
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[make-same-domains (-> (listof variable?) generic-set? domain-mapping/c)]
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2020-02-23 00:15:18 +01:00
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[make-boolean-domains (-> (listof variable?) (hash/c variable? (list/c #f #t)))]
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2020-02-23 20:13:37 +01:00
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[build-all-boolean-states (-> (listof variable?) (listof state?))]
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2020-03-22 20:43:14 +01:00
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[get-interaction-sign (-> network? domain-mapping/c variable? variable? (or/c '+ '- '0))]
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2020-03-22 20:45:11 +01:00
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[build-signed-interaction-graph/form (-> network-form? domain-mapping/c graph?)]
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[build-boolean-signed-interaction-graph/form (-> network-form? graph?)]
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2020-03-22 21:00:12 +01:00
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[build-signed-interaction-graph (-> network? domain-mapping/c graph?)]
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[build-boolean-signed-interaction-graph (-> network? graph?)]
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2020-02-23 11:25:19 +01:00
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[make-asyn (-> (listof variable?) mode?)]
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2020-02-23 11:42:01 +01:00
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[make-syn (-> (listof variable?) mode?)]
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[make-dynamics-from-func (-> network? (-> (listof variable?) mode?) dynamics?)]
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[make-asyn-dynamics (-> network? dynamics?)]
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2020-02-23 12:19:47 +01:00
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[make-syn-dynamics (-> network? dynamics?)]
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2020-03-04 18:54:36 +01:00
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[read-org-network-make-asyn (-> string? dynamics?)]
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[read-org-network-make-syn (-> string? dynamics?)]
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2020-02-23 13:28:51 +01:00
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[dds-step-one (-> dynamics? state? (set/c state?))]
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2020-02-23 14:11:55 +01:00
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[dds-step-one-annotated (-> dynamics? state? (set/c (cons/c modality? state?)))]
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2020-02-23 18:51:57 +01:00
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[dds-step (-> dynamics? (set/c state? #:kind 'dont-care) (set/c state?))]
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[dds-build-state-graph (-> dynamics? (set/c state? #:kind 'dont-care) graph?)]
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2020-02-23 19:24:53 +01:00
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[dds-build-n-step-state-graph (-> dynamics? (set/c state? #:kind 'dont-care) number? graph?)]
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2020-02-28 21:46:25 +01:00
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[dds-build-state-graph-annotated (-> dynamics? (set/c state? #:kind 'dont-care) graph?)]
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[dds-build-n-step-state-graph-annotated (-> dynamics? (set/c state? #:kind 'dont-care) number? graph?)]
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2020-02-23 19:44:55 +01:00
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[pretty-print-state (-> state? string?)]
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[pretty-print-boolean-state (-> state? string?)]
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[pretty-print-state-graph-with (-> graph? (-> state? string?) graph?)]
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[pretty-print-state-graph (-> graph? graph?)]
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2020-05-28 00:49:29 +02:00
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[ppsg (-> graph? graph?)]
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2020-02-23 20:13:37 +01:00
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[pretty-print-boolean-state-graph (-> graph? graph?)]
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2020-05-28 00:49:29 +02:00
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[ppsgb (-> graph? graph?)]
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2020-02-28 21:56:42 +01:00
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[build-full-boolean-state-graph (-> dynamics? graph?)]
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2020-03-15 16:12:35 +01:00
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[build-full-boolean-state-graph-annotated (-> dynamics? graph?)]
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2020-03-22 14:34:40 +01:00
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[tabulate-state (->* (procedure? domain-mapping/c) (#:headers boolean?)
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(listof (listof any/c)))]
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2020-06-02 21:53:53 +02:00
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[tabulate-state* (->* ((non-empty-listof procedure?) domain-mapping/c) (#:headers boolean?)
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(listof (listof any/c)))]
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2020-03-22 14:34:40 +01:00
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[tabulate-state/boolean (->* (procedure? (listof variable?)) (#:headers boolean?)
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(listof (listof any/c)))]
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2020-06-02 21:53:53 +02:00
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[tabulate-state*/boolean (->* ((non-empty-listof procedure?) (listof variable?)) (#:headers boolean?)
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(listof (listof any/c)))]
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2020-03-22 19:22:54 +01:00
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[tabulate-network (->* (network? domain-mapping/c) (#:headers boolean?)
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(listof (listof any/c)))]
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[tabulate-boolean-network (->* (network?) (#:headers boolean?)
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(listof (listof any/c)))]
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2020-03-24 00:18:39 +01:00
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[table->network (->* ((listof (*list/c any/c any/c))) (#:headers boolean?) network?)]
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2020-03-22 14:35:26 +01:00
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[random-function/state (domain-mapping/c generic-set? . -> . procedure?)]
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2020-03-22 19:28:44 +01:00
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[random-boolean-function/state ((listof variable?) . -> . procedure?)]
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[random-network (domain-mapping/c . -> . network?)]
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[random-boolean-network ((listof variable?) . -> . network?)]
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2020-07-22 23:46:58 +02:00
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[random-boolean-network/vars (number? . -> . network?)]
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2020-08-01 23:38:24 +02:00
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[apply-tbf-to-state (-> tbf? state? (or/c 0 1))]
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2020-07-23 00:11:14 +02:00
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[tbf/state-w (-> tbf/state? (hash/c variable? number?))]
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[tbf/state-θ (-> tbf/state? number?)]
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2020-07-23 00:19:25 +02:00
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[make-tbf/state (-> (listof (cons/c variable? number?)) number? tbf/state?)]
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2020-10-10 23:23:43 +02:00
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[apply-tbf/state (-> tbf/state? (hash/c variable? (or/c 0 1)) (or/c 0 1))]
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[lists->tbfs/state (->* ((listof (listof (or/c number? symbol?))))
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(#:headers boolean?)
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(listof tbf/state?))])
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2020-02-20 14:13:48 +01:00
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;; Predicates
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(contract-out [variable? (-> any/c boolean?)]
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[state? (-> any/c boolean?)]
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[update-function-form? (-> any/c boolean?)]
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2020-02-23 11:10:18 +01:00
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[network-form? (-> any/c boolean?)]
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2020-02-23 13:53:02 +01:00
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[modality? (-> any/c boolean?)]
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2020-02-23 11:10:18 +01:00
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[mode? (-> any/c boolean?)])
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2020-02-20 00:56:30 +01:00
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;; Contracts
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2020-02-22 10:37:37 +01:00
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(contract-out [state/c contract?]
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2020-02-23 09:12:01 +01:00
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[update-function/c contract?]
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2020-07-22 23:45:13 +02:00
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[domain-mapping/c contract?]
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[tbn? contract?]))
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2020-02-20 00:56:30 +01:00
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2020-05-22 23:40:40 +02:00
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(module+ test
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2020-05-27 23:39:38 +02:00
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(require rackunit))
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2020-05-22 23:40:40 +02:00
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2020-02-20 00:56:30 +01:00
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;;; =================
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;;; Basic definitions
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;;; =================
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(define variable? symbol?)
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;;; A state of a network is a mapping from the variables of the
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;;; network to their values.
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(define state? variable-mapping?)
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(define state/c (flat-named-contract 'state state?))
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;;; An update function is a function computing a value from the given
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;;; state.
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2020-02-20 14:13:48 +01:00
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(define update-function/c (-> state? any/c))
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2020-02-20 00:56:30 +01:00
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;;; A network is a mapping from its variables to its update functions.
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2020-03-21 19:19:23 +01:00
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(define network? (hash/c variable? procedure?))
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2020-02-20 00:56:30 +01:00
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;;; Given a state s updates all the variables from xs. This
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;;; corresponds to a parallel mode.
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2020-02-23 09:19:45 +01:00
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(define (update network s xs)
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(for/fold ([new-s s])
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([x xs])
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(let ([f (hash-ref network x)])
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(hash-set new-s x (f s)))))
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2020-02-20 00:56:30 +01:00
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2020-05-22 23:40:40 +02:00
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(module+ test
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2020-05-27 23:39:38 +02:00
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(test-case "basic definitions"
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(define f1 (λ (s) (let ([x1 (hash-ref s 'x1)]
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[x2 (hash-ref s 'x2)])
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(and x1 (not x2)))))
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(define f2 (λ (s) (let ([x2 (hash-ref s 'x2)])
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(not x2))))
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(define bn (make-network-from-functions `((x1 . ,f1) (x2 . ,f2))))
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(define s1 (make-state '((x1 . #t) (x2 . #f))))
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(define new-s1 (update bn s1 '(x2 x1)))
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(define s2 (make-state '((x1 . #f) (x2 . #f))))
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(define new-s2 (update bn s2 '(x2)))
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2020-05-22 23:40:40 +02:00
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(check-equal? s1 #hash((x1 . #t) (x2 . #f)))
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(check-equal? new-s1 #hash((x1 . #t) (x2 . #t)))
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(check-equal? s2 #hash((x1 . #f) (x2 . #f)))
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(check-equal? new-s2 #hash((x1 . #f) (x2 . #t)))))
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2020-02-23 08:47:16 +01:00
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;;; A version of make-immutable-hash restricted to creating network
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;;; states (see contract).
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2020-02-22 23:20:10 +01:00
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(define (make-state mappings) (make-immutable-hash mappings))
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2020-02-20 00:56:30 +01:00
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2020-02-26 15:51:25 +01:00
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;;; Makes a new Boolean states from a state with numerical values 0
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;;; and 1.
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(define (make-state-booleanize mappings)
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(make-state (for/list ([mp mappings])
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(match mp
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[(cons var 0) (cons var #f)]
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[(cons var 1) (cons var #t)]))))
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2020-05-22 23:40:40 +02:00
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(module+ test
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2020-05-27 23:39:38 +02:00
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(test-case "make-state, make-state-booleanize, booleanize-state"
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(check-equal? (make-state-booleanize '((a . 0) (b . 1)))
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(make-state '((a . #f) (b . #t))))
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(check-equal? (booleanize-state (make-state '((a . 0) (b . 1))))
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(make-state '((a . #f) (b . #t))))))
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2020-05-22 23:40:40 +02:00
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2020-02-26 20:47:38 +01:00
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;;; Booleanizes a given state: replaces 0 with #f and 1 with #t.
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(define (booleanize-state s)
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(for/hash ([(x val) s]) (match val [0 (values x #f)] [1 (values x #t)])))
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2020-02-23 08:47:16 +01:00
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;;; A version of make-immutable-hash restricted to creating networks.
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2020-02-22 23:22:43 +01:00
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(define (make-network-from-functions funcs) (make-immutable-hash funcs))
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2020-02-20 00:56:30 +01:00
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;;; =================================
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;;; Syntactic description of networks
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;;; =================================
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;;; An update function form is any form which can appear as a body of
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;;; a function and which can be evaluated with eval. For example,
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;;; '(and x y (not z)) or '(+ 1 a (- b 10)).
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(define update-function-form? any/c)
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;;; A Boolean network form is a mapping from its variables to the
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;;; forms of their update functions.
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(define network-form? variable-mapping?)
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;;; Build an update function from an update function form.
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(define (update-function-form->update-function form)
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2020-02-20 15:36:29 +01:00
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(λ (s) (eval-with s form)))
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2020-02-20 00:56:30 +01:00
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2020-05-22 23:40:40 +02:00
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(module+ test
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2020-05-27 23:39:38 +02:00
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(test-case "update-function-form->update-function"
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(define s (make-state '((x . #t) (y . #f))))
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(define f (update-function-form->update-function '(and x y)))
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2020-05-22 23:40:40 +02:00
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(check-equal? (f s) #f)))
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2020-02-20 00:56:30 +01:00
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;;; Build a network from a network form.
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(define (network-form->network bnf)
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2020-02-23 08:57:50 +01:00
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(for/hash ([(x form) bnf])
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(values x (update-function-form->update-function form))))
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2020-02-20 00:56:30 +01:00
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2020-05-22 23:40:40 +02:00
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(module+ test
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2020-05-27 23:39:38 +02:00
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(test-case "network-form->network"
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(define bn (network-form->network
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(make-hash '((a . (and a b)) (b . (not b))))))
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(define s (make-state '((a . #t) (b . #t))))
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2020-05-22 23:40:40 +02:00
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(check-equal? ((hash-ref bn 'a) s) #t)))
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2020-02-20 00:56:30 +01:00
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;;; Build a network from a list of pairs of forms of update functions.
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(define (make-network-from-forms forms)
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2020-02-22 23:22:43 +01:00
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(network-form->network (make-immutable-hash forms)))
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2020-02-20 00:56:30 +01:00
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2020-05-22 23:40:40 +02:00
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(module+ test
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2020-05-27 23:39:38 +02:00
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(test-case "make-network-from-forms"
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(define bn (make-network-from-forms '((a . (and a b))
|
|
|
|
|
(b . (not b)))))
|
|
|
|
|
(define s (make-state '((a . #t) (b . #t))))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(check-equal? ((hash-ref bn 'a) s) #t)))
|
|
|
|
|
|
2020-02-20 00:56:30 +01:00
|
|
|
|
|
|
|
|
|
;;; ============================
|
|
|
|
|
;;; Inferring interaction graphs
|
|
|
|
|
;;; ============================
|
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|
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|
|
|
|
|
|
;;; I allow any syntactic forms in definitions of Boolean functions.
|
|
|
|
|
;;; I can still find out which Boolean variables appear in those
|
|
|
|
|
;;; syntactic form, but I have no reliable syntactic means of finding
|
|
|
|
|
;;; out what kind of action do they have (inhibition or activation)
|
|
|
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|
;;; since I cannot do Boolean minimisation (e.g., I cannot rely on not
|
|
|
|
|
;;; appearing before a variable, since (not (not a)) is equivalent
|
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|
|
|
;;; to a). On the other hand, going through all Boolean states is
|
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|
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|
;;; quite resource-consuming and thus not always useful.
|
|
|
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|
;;;
|
|
|
|
|
;;; In this section I provide inference of both unsigned and signed
|
|
|
|
|
;;; interaction graphs, but since the inference of signed interaction
|
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|
;;; graphs is based on analysing the dynamics of the networks, it may
|
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|
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|
;;; be quite resource-consuming.
|
2020-02-20 15:17:32 +01:00
|
|
|
|
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|
;;; Lists the variables of the network form appearing in the update
|
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|
;;; function form for x.
|
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|
|
|
(define (list-interactions nf x)
|
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|
|
|
(set-intersect
|
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|
|
|
(extract-symbols (hash-ref nf x))
|
|
|
|
|
(hash-keys nf)))
|
2020-02-20 15:56:48 +01:00
|
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|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "list-interactions"
|
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|
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|
(define n #hash((a . (+ a b c))
|
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|
|
|
(b . (- b c))))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(check-true (set=? (list-interactions n 'a) '(a b)))
|
|
|
|
|
(check-true (set=? (list-interactions n 'b) '(b)))))
|
|
|
|
|
|
2020-02-20 15:56:48 +01:00
|
|
|
|
;;; Builds the graph in which the vertices are the variables of a
|
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|
|
;;; given network, and which contains an arrow from a to b whenever a
|
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|
|
;;; appears in (list-interactions a).
|
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|
|
|
(define (build-interaction-graph n)
|
|
|
|
|
(transpose
|
|
|
|
|
(unweighted-graph/adj
|
2020-02-23 08:57:50 +01:00
|
|
|
|
(for/list ([(var _) n]) (cons var (list-interactions n var))))))
|
2020-02-22 22:27:40 +01:00
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "build-interaction-graph"
|
|
|
|
|
(define n #hash((a . (+ a b c))
|
|
|
|
|
(b . (- b c))))
|
|
|
|
|
(define ig (build-interaction-graph n))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(check-true (has-vertex? ig 'a))
|
|
|
|
|
(check-true (has-vertex? ig 'b))
|
|
|
|
|
(check-false (has-vertex? ig 'c))
|
|
|
|
|
(check-true (has-edge? ig 'a 'a))
|
|
|
|
|
(check-true (has-edge? ig 'b 'a))
|
|
|
|
|
(check-true (has-edge? ig 'b 'b))
|
|
|
|
|
(check-false (has-edge? ig 'c 'b))
|
|
|
|
|
(check-false (has-edge? ig 'c 'a))))
|
|
|
|
|
|
2020-02-23 09:12:01 +01:00
|
|
|
|
;;; A domain mapping is a hash set mapping variables to the lists of
|
|
|
|
|
;;; values in their domains.
|
|
|
|
|
(define domain-mapping/c (hash/c variable? list?))
|
|
|
|
|
|
2020-02-23 09:09:43 +01:00
|
|
|
|
;;; Given a hash-set mapping variables to generic sets of their
|
2020-02-22 22:27:40 +01:00
|
|
|
|
;;; possible values, constructs the list of all possible states.
|
|
|
|
|
(define (build-all-states vars-domains)
|
2020-03-22 19:34:08 +01:00
|
|
|
|
(let* ([var-dom-list (hash-map vars-domains (λ (x y) (cons x y)) #t)]
|
2020-02-23 09:09:43 +01:00
|
|
|
|
[vars (map car var-dom-list)]
|
|
|
|
|
[domains (map cdr var-dom-list)])
|
2020-02-22 22:27:40 +01:00
|
|
|
|
(for/list ([s (apply cartesian-product domains)])
|
|
|
|
|
(make-state (for/list ([var vars] [val s])
|
|
|
|
|
(cons var val))))))
|
2020-02-22 22:41:56 +01:00
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "build-all-states"
|
|
|
|
|
(check-equal? (build-all-states #hash((a . (#t #f)) (b . (1 2 3))))
|
|
|
|
|
'(#hash((a . #t) (b . 1))
|
|
|
|
|
#hash((a . #t) (b . 2))
|
|
|
|
|
#hash((a . #t) (b . 3))
|
|
|
|
|
#hash((a . #f) (b . 1))
|
|
|
|
|
#hash((a . #f) (b . 2))
|
|
|
|
|
#hash((a . #f) (b . 3))))))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
|
2020-02-23 00:13:36 +01:00
|
|
|
|
;;; Makes a hash set mapping all variables to a single domain.
|
2020-02-23 00:15:18 +01:00
|
|
|
|
(define (make-same-domains vars domain)
|
2020-02-23 08:57:50 +01:00
|
|
|
|
(for/hash ([var vars]) (values var domain)))
|
2020-02-23 00:13:36 +01:00
|
|
|
|
|
|
|
|
|
;;; Makes a hash set mapping all variables to the Boolean domain.
|
2020-02-23 00:15:18 +01:00
|
|
|
|
(define (make-boolean-domains vars)
|
|
|
|
|
(make-same-domains vars '(#f #t)))
|
2020-02-23 00:13:36 +01:00
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "make-same-domains, make-boolean-domains"
|
|
|
|
|
(check-equal? (make-boolean-domains '(a b))
|
|
|
|
|
#hash((a . (#f #t)) (b . (#f #t))))))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
|
2020-02-23 20:13:37 +01:00
|
|
|
|
;;; Builds all boolean states possible over a given set of variables.
|
|
|
|
|
(define (build-all-boolean-states vars)
|
|
|
|
|
(build-all-states (make-boolean-domains vars)))
|
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "build-all-boolean-states"
|
|
|
|
|
(check-equal? (build-all-boolean-states '(a b))
|
|
|
|
|
'(#hash((a . #f) (b . #f))
|
|
|
|
|
#hash((a . #f) (b . #t))
|
|
|
|
|
#hash((a . #t) (b . #f))
|
|
|
|
|
#hash((a . #t) (b . #t))))))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
|
2020-03-22 20:43:14 +01:00
|
|
|
|
;;; Given two interacting variables of a network and the domains
|
2020-02-23 00:04:19 +01:00
|
|
|
|
;;; of the variables, returns '+ if the interaction is monotonously
|
|
|
|
|
;;; increasing, '- if it is monotonously decreasing, and '0 otherwise.
|
|
|
|
|
;;;
|
|
|
|
|
;;; This function does not check whether the two variables indeed
|
|
|
|
|
;;; interact. Its behaviour is undefined if the variables do not
|
|
|
|
|
;;; interact.
|
|
|
|
|
;;;
|
|
|
|
|
;;; /!\ This function iterates through almost all of the states of the
|
|
|
|
|
;;; network, so its performance decreases very quickly with network
|
|
|
|
|
;;; size.
|
2020-03-22 20:43:14 +01:00
|
|
|
|
(define (get-interaction-sign network doms x y)
|
2020-02-23 00:04:19 +01:00
|
|
|
|
(let* ([dom-x (hash-ref doms x)]
|
|
|
|
|
[dom-y (hash-ref doms y)]
|
|
|
|
|
;; Replace the domain of x by a dummy singleton.
|
|
|
|
|
[doms-no-x (hash-set doms x '(#f))]
|
|
|
|
|
;; Build all the states, but as if x were not there: since I
|
|
|
|
|
;; replace its domain by a singleton, all states will contain
|
|
|
|
|
;; the same value for x.
|
2020-02-23 09:09:43 +01:00
|
|
|
|
[states-no-x (build-all-states doms-no-x)]
|
2020-02-23 00:04:19 +01:00
|
|
|
|
;; Go through all states, then through all ordered pairs of
|
|
|
|
|
;; values of x, generate pairs of states (s1, s2) such that x
|
|
|
|
|
;; has a smaller value in s1, and check that updating y in s1
|
|
|
|
|
;; yields a smaller value than updating y in s2. I rely on
|
|
|
|
|
;; the fact that the domains are ordered.
|
|
|
|
|
[x-y-interactions (for*/list ([s states-no-x]
|
|
|
|
|
[x1 dom-x] ; ordered pairs of values of x
|
|
|
|
|
[x2 (cdr (member x1 dom-x))])
|
|
|
|
|
(let* ([s1 (hash-set s x x1)] ; s1(x) < s2(x)
|
|
|
|
|
[s2 (hash-set s x x2)]
|
|
|
|
|
[y1 ((hash-ref network y) s1)]
|
|
|
|
|
[y2 ((hash-ref network y) s2)])
|
|
|
|
|
;; y1 <= y2?
|
|
|
|
|
(<= (index-of dom-y y1) (index-of dom-y y2))))])
|
|
|
|
|
(cond
|
|
|
|
|
;; If, in all interactions, y1 <= y2, then we have an
|
|
|
|
|
;; increasing/promoting interaction between x and y.
|
|
|
|
|
[(andmap (λ (x) (eq? x #t)) x-y-interactions) '+]
|
|
|
|
|
;; If, in all interactions, y1 > y2, then we have an
|
|
|
|
|
;; decreasing/inhibiting interaction between x and y.
|
|
|
|
|
[(andmap (λ (x) (eq? x #f)) x-y-interactions) '-]
|
|
|
|
|
;; Otherwise the interaction is neither increasing nor
|
|
|
|
|
;; decreasing.
|
|
|
|
|
[else '0])))
|
2020-02-23 01:00:09 +01:00
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "get-interaction-sign"
|
|
|
|
|
(define n #hash((a . (not b)) (b . a)))
|
|
|
|
|
(define doms (make-boolean-domains '(a b)))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(check-equal? (get-interaction-sign (network-form->network n) doms 'a 'b) '+)
|
|
|
|
|
(check-equal? (get-interaction-sign (network-form->network n) doms 'b 'a) '-)))
|
|
|
|
|
|
2020-02-23 01:00:09 +01:00
|
|
|
|
;;; Constructs a signed interaction graph of a given network form,
|
|
|
|
|
;;; given the ordered domains of its variables. The order on the
|
|
|
|
|
;;; domains determines the signs which will appear on the interaction
|
|
|
|
|
;;; graph.
|
|
|
|
|
;;;
|
|
|
|
|
;;; /!\ This function iterates through almost all states of the
|
|
|
|
|
;;; network for every arrow in the unsigned interaction graph, so its
|
|
|
|
|
;;; performance decreases very quickly with the size of the network.
|
2020-03-22 20:45:11 +01:00
|
|
|
|
(define (build-signed-interaction-graph/form network-form doms)
|
2020-03-22 20:43:14 +01:00
|
|
|
|
(let ([ig (build-interaction-graph network-form)]
|
|
|
|
|
[network (network-form->network network-form)])
|
2020-05-14 01:06:17 +02:00
|
|
|
|
;; Label every edge of the interaction graph with the sign.
|
|
|
|
|
(define sig
|
|
|
|
|
(weighted-graph/directed
|
|
|
|
|
(for/list ([e (in-edges ig)])
|
|
|
|
|
(match-let ([(list x y) e])
|
|
|
|
|
(list (get-interaction-sign network doms x y)
|
|
|
|
|
x y)))))
|
|
|
|
|
;; Ensure that every variable of the network appears in the signed
|
|
|
|
|
;; interaction graph as well.
|
|
|
|
|
(for ([v (in-vertices ig)])
|
|
|
|
|
(add-vertex! sig v))
|
|
|
|
|
sig))
|
2020-02-23 10:00:48 +01:00
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "build-signed-interaction-graph/form"
|
|
|
|
|
(define n #hash((a . (not b)) (b . a)))
|
|
|
|
|
(define doms (make-boolean-domains '(a b)))
|
|
|
|
|
(define sig1 (build-signed-interaction-graph/form n doms))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(check-true (has-vertex? sig1 'a))
|
|
|
|
|
(check-true (has-vertex? sig1 'b))
|
|
|
|
|
(check-false (has-vertex? sig1 'c))
|
|
|
|
|
(check-false (has-edge? sig1 'a 'a))
|
|
|
|
|
(check-true (has-edge? sig1 'b 'a))
|
|
|
|
|
(check-false (has-edge? sig1 'b 'b))
|
|
|
|
|
(check-false (has-edge? sig1 'c 'b))
|
|
|
|
|
(check-false (has-edge? sig1 'c 'a))
|
|
|
|
|
(check-equal? (edge-weight sig1 'a 'b) '+)
|
|
|
|
|
(check-equal? (edge-weight sig1 'b 'a) '-)))
|
|
|
|
|
|
2020-02-23 10:00:48 +01:00
|
|
|
|
;;; Calls build-signed-interaction-graph with the Boolean domain for
|
|
|
|
|
;;; all variable.
|
|
|
|
|
;;;
|
|
|
|
|
;;; /!\ The same performance warning applies as for
|
|
|
|
|
;;; build-signed-interaction-graph.
|
2020-03-22 20:45:11 +01:00
|
|
|
|
(define (build-boolean-signed-interaction-graph/form network-form)
|
|
|
|
|
(build-signed-interaction-graph/form
|
|
|
|
|
network-form
|
|
|
|
|
(make-boolean-domains (hash-keys network-form))))
|
2020-02-23 11:10:18 +01:00
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "build-boolean-signed-interaction-graph/form"
|
|
|
|
|
(define n #hash((a . (not b)) (b . a)))
|
|
|
|
|
(define sig2 (build-boolean-signed-interaction-graph/form n))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(check-true (has-vertex? sig2 'a))
|
|
|
|
|
(check-true (has-vertex? sig2 'b))
|
|
|
|
|
(check-false (has-vertex? sig2 'c))
|
|
|
|
|
(check-false (has-edge? sig2 'a 'a))
|
|
|
|
|
(check-true (has-edge? sig2 'b 'a))
|
|
|
|
|
(check-false (has-edge? sig2 'b 'b))
|
|
|
|
|
(check-false (has-edge? sig2 'c 'b))
|
|
|
|
|
(check-false (has-edge? sig2 'c 'a))
|
|
|
|
|
(check-equal? (edge-weight sig2 'a 'b) '+)
|
|
|
|
|
(check-equal? (edge-weight sig2 'b 'a) '-)))
|
|
|
|
|
|
2020-03-22 21:00:12 +01:00
|
|
|
|
;;; Similar to build-signed-interaction-graph/form, but operates on a
|
|
|
|
|
;;; network rather than a form. The resulting graph only includes the
|
|
|
|
|
;;; edges for positive or negative interactions.
|
|
|
|
|
;;;
|
|
|
|
|
;;; This function has operates with much less knowledge than
|
|
|
|
|
;;; build-signed-interaction-graph/form, so prefer using the latter
|
|
|
|
|
;;; when you can get a network form.
|
|
|
|
|
;;;
|
|
|
|
|
;;; /!\ This function iterates through all states of the network for
|
|
|
|
|
;;; every arrow in the unsigned interaction graph, so its performance
|
|
|
|
|
;;; decreases very quickly with the size of the network.
|
|
|
|
|
(define (build-signed-interaction-graph network doms)
|
2020-05-14 01:06:17 +02:00
|
|
|
|
(define sig
|
|
|
|
|
(weighted-graph/directed
|
|
|
|
|
(for*/fold ([edges '()])
|
|
|
|
|
([(x _) (in-hash network)]
|
|
|
|
|
[(y _) (in-hash network)])
|
|
|
|
|
(match (get-interaction-sign network doms x y)
|
|
|
|
|
['0 edges]
|
|
|
|
|
[sign (cons (list sign x y) edges)]))))
|
|
|
|
|
;; Ensure that all variables of the network appear in the signed
|
|
|
|
|
;; interaction graph.
|
|
|
|
|
(for ([(v _) (in-hash network)])
|
|
|
|
|
(add-vertex! sig v))
|
|
|
|
|
sig)
|
2020-03-22 21:00:12 +01:00
|
|
|
|
|
|
|
|
|
;;; Calls build-signed-interaction-graph assuming that the domains of
|
|
|
|
|
;;; all variables are Boolean.
|
|
|
|
|
;;;
|
|
|
|
|
;;; This function has operates with much less knowledge than
|
|
|
|
|
;;; build-boolean-signed-interaction-graph/form, so prefer using the
|
|
|
|
|
;;; latter when you can get a network form.
|
|
|
|
|
;;;
|
|
|
|
|
;;; /!\ This function iterates through all states of the network for
|
|
|
|
|
;;; every arrow in the unsigned interaction graph, so its performance
|
|
|
|
|
;;; decreases very quickly with the size of the network.
|
|
|
|
|
(define (build-boolean-signed-interaction-graph network)
|
|
|
|
|
(build-signed-interaction-graph network (make-boolean-domains (hash-keys network))))
|
2020-02-23 11:10:18 +01:00
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "build-signed-interaction-graph, build-boolean-signed-interaction-graph"
|
|
|
|
|
(define n #hash((a . (not b)) (b . a)))
|
|
|
|
|
(define sig3 (build-boolean-signed-interaction-graph (network-form->network n)))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(check-true (has-vertex? sig3 'a))
|
|
|
|
|
(check-true (has-vertex? sig3 'b))
|
|
|
|
|
(check-equal? (edge-weight sig3 'a 'a) '+)
|
|
|
|
|
(check-equal? (edge-weight sig3 'b 'b) '+)
|
|
|
|
|
(check-equal? (edge-weight sig3 'a 'b) '+)
|
|
|
|
|
(check-equal? (edge-weight sig3 'b 'a) '-)))
|
|
|
|
|
|
|
|
|
|
;;; Interaction graphs for networks without interactions must still
|
2020-05-27 23:39:38 +02:00
|
|
|
|
;;; contain all nodes.
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "Interaction must graphs always contain all nodes."
|
|
|
|
|
(define n #hash((a . #t) (b . #t)))
|
|
|
|
|
(define ig (build-interaction-graph n))
|
|
|
|
|
(define sig-nf (build-boolean-signed-interaction-graph/form n))
|
|
|
|
|
(define sig (build-boolean-signed-interaction-graph (network-form->network n)))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(check-equal? (get-vertices ig) '(b a))
|
|
|
|
|
(check-true (empty? (get-edges ig)))
|
|
|
|
|
(check-equal? (get-vertices sig-nf) '(b a))
|
|
|
|
|
(check-true (empty? (get-edges sig-nf)))
|
|
|
|
|
(check-equal? (get-vertices sig) '(b a))))
|
|
|
|
|
|
|
|
|
|
|
2020-02-23 11:10:18 +01:00
|
|
|
|
;;; ====================
|
|
|
|
|
;;; Dynamics of networks
|
|
|
|
|
;;; ====================
|
|
|
|
|
|
|
|
|
|
;;; This section contains definitions for building and analysing the
|
|
|
|
|
;;; dynamics of networks.
|
|
|
|
|
|
2020-02-23 13:53:02 +01:00
|
|
|
|
;;; A modality is a set of variable.
|
|
|
|
|
(define modality? (set/c variable?))
|
|
|
|
|
|
|
|
|
|
;;; A mode is a set of modalities.
|
|
|
|
|
(define mode? (set/c modality?))
|
2020-02-23 11:10:18 +01:00
|
|
|
|
|
|
|
|
|
;;; A network dynamics is a network plus a mode.
|
2020-02-23 12:19:47 +01:00
|
|
|
|
(struct dynamics (network mode)
|
|
|
|
|
#:methods gen:dds
|
2020-03-02 12:12:57 +01:00
|
|
|
|
[;; Annotates each result state with the modality which lead to it.
|
2020-02-23 14:11:55 +01:00
|
|
|
|
(define/match (dds-step-one-annotated dyn s)
|
|
|
|
|
[((dynamics network mode) s)
|
|
|
|
|
(for/set ([m mode]) (cons m (update network s m)))])])
|
2020-02-23 11:25:19 +01:00
|
|
|
|
|
|
|
|
|
;;; Given a list of variables, builds the asynchronous mode (a set of
|
|
|
|
|
;;; singletons).
|
|
|
|
|
(define (make-asyn vars)
|
|
|
|
|
(for/set ([v vars]) (set v)))
|
|
|
|
|
|
|
|
|
|
;;; Given a list of variables, builds the synchronous mode (a set
|
|
|
|
|
;;; containing the set of variables).
|
|
|
|
|
(define (make-syn vars) (set (list->set vars)))
|
2020-02-23 11:42:01 +01:00
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "make-asyn, make-syn"
|
|
|
|
|
(define vars '(a b c))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(check-equal? (make-asyn vars) (set (set 'a) (set 'b) (set 'c)))
|
|
|
|
|
(check-equal? (make-syn vars) (set (set 'a 'b 'c)))))
|
|
|
|
|
|
2020-02-23 11:42:01 +01:00
|
|
|
|
;;; Given a network, applies a function for building a mode to its
|
|
|
|
|
;;; variables and returns the corresponding network dynamics.
|
|
|
|
|
(define (make-dynamics-from-func network mode-func)
|
|
|
|
|
(dynamics network (mode-func (hash-keys network))))
|
|
|
|
|
|
|
|
|
|
;;; Creates the asynchronous dynamics for a given network.
|
|
|
|
|
(define (make-asyn-dynamics network)
|
|
|
|
|
(make-dynamics-from-func network make-asyn))
|
|
|
|
|
|
|
|
|
|
;;; Creates the synchronous dynamics for a given network.
|
|
|
|
|
(define (make-syn-dynamics network)
|
|
|
|
|
(make-dynamics-from-func network make-syn))
|
2020-02-23 19:24:53 +01:00
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "make-asyn-dynamics, make-syn-dynamics"
|
|
|
|
|
(define n (network-form->network #hash((a . (not a)) (b . b))))
|
|
|
|
|
(define asyn (make-asyn-dynamics n))
|
|
|
|
|
(define syn (make-syn-dynamics n))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(check-equal? (dynamics-network asyn) n)
|
|
|
|
|
(check-equal? (dynamics-mode asyn) (set (set 'a) (set 'b)))
|
|
|
|
|
(check-equal? (dynamics-network syn) n)
|
|
|
|
|
(check-equal? (dynamics-mode syn) (set (set 'a 'b)))))
|
|
|
|
|
|
2020-03-04 18:54:36 +01:00
|
|
|
|
;;; Reads an Org-mode-produced sexp, converts it into a network, and
|
|
|
|
|
;;; builds the asyncronous dynamics out of it.
|
|
|
|
|
(define read-org-network-make-asyn (compose make-asyn-dynamics network-form->network read-org-variable-mapping))
|
|
|
|
|
|
|
|
|
|
;;; Reads an Org-mode-produced sexp, converts it into a network, and
|
|
|
|
|
;;; builds the synchronous dynamics out of it.
|
|
|
|
|
(define read-org-network-make-syn (compose make-syn-dynamics network-form->network read-org-variable-mapping))
|
|
|
|
|
|
2020-02-23 19:24:53 +01:00
|
|
|
|
;;; Pretty-prints a state of the network.
|
|
|
|
|
(define (pretty-print-state s)
|
2020-02-26 21:27:02 +01:00
|
|
|
|
(string-join (hash-map s (λ (key val) (format "~a:~a" key val)) #t)))
|
2020-02-23 19:44:55 +01:00
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "pretty-print-state"
|
|
|
|
|
(check-equal? (pretty-print-state (make-state '((a . #f) (b . 3) (c . 4))))
|
|
|
|
|
"a:#f b:3 c:4")))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
|
2020-02-23 19:44:55 +01:00
|
|
|
|
;;; Pretty-prints a state of the network to Boolean values 0 or 1.
|
|
|
|
|
(define (pretty-print-boolean-state s)
|
2020-06-06 08:23:55 +02:00
|
|
|
|
(string-join (hash-map s (λ (key val) (format "~a:~a" key (any->01 val))) #t)))
|
2020-02-23 19:44:55 +01:00
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "pretty-print-boolean-state"
|
|
|
|
|
(check-equal?
|
|
|
|
|
(pretty-print-boolean-state (make-state '((a . #f) (b . #t) (c . #t))))
|
|
|
|
|
"a:0 b:1 c:1")))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
|
2020-02-23 19:44:55 +01:00
|
|
|
|
;;; Given a state graph and a pretty-printer for states build a new
|
2020-03-01 15:20:44 +01:00
|
|
|
|
;;; state graph with pretty-printed vertices and edges.
|
2020-02-23 19:44:55 +01:00
|
|
|
|
(define (pretty-print-state-graph-with gr pprinter)
|
2020-03-02 23:59:37 +01:00
|
|
|
|
(update-graph gr #:v-func pprinter #:e-func pretty-print-set-sets))
|
2020-02-23 19:44:55 +01:00
|
|
|
|
|
|
|
|
|
;;; Pretty prints a state graph with pretty-print-state.
|
|
|
|
|
(define (pretty-print-state-graph gr)
|
|
|
|
|
(pretty-print-state-graph-with gr pretty-print-state))
|
|
|
|
|
|
|
|
|
|
;;; A shortcut for pretty-print-state-graph.
|
2020-05-28 00:49:29 +02:00
|
|
|
|
(define ppsg pretty-print-state-graph)
|
2020-02-23 19:44:55 +01:00
|
|
|
|
|
|
|
|
|
;;; Pretty prints a state graph with pretty-print-boolean-state.
|
|
|
|
|
(define (pretty-print-boolean-state-graph gr)
|
|
|
|
|
(pretty-print-state-graph-with gr pretty-print-boolean-state))
|
|
|
|
|
|
|
|
|
|
;;; A shortcut for pretty-print-boolean-state-graph.
|
2020-05-28 00:49:29 +02:00
|
|
|
|
(define ppsgb pretty-print-boolean-state-graph)
|
2020-02-23 20:13:37 +01:00
|
|
|
|
|
|
|
|
|
;;; Builds the full state graph of a Boolean network.
|
|
|
|
|
(define (build-full-boolean-state-graph dyn)
|
|
|
|
|
(dds-build-state-graph
|
|
|
|
|
dyn
|
|
|
|
|
(list->set (build-all-boolean-states (hash-keys (dynamics-network dyn))))))
|
2020-02-28 21:56:42 +01:00
|
|
|
|
|
|
|
|
|
;;; Build the full annotated state graph of a Boolean network.
|
|
|
|
|
(define (build-full-boolean-state-graph-annotated dyn)
|
|
|
|
|
(dds-build-state-graph-annotated
|
|
|
|
|
dyn
|
|
|
|
|
(list->set (build-all-boolean-states (hash-keys (dynamics-network dyn))))))
|
2020-03-15 16:12:35 +01:00
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "Dynamics of networks"
|
|
|
|
|
(define n (network-form->network #hash((a . (not a)) (b . b))))
|
|
|
|
|
(define asyn (make-asyn-dynamics n))
|
|
|
|
|
(define syn (make-syn-dynamics n))
|
|
|
|
|
(define s (make-state '((a . #t) (b . #f))))
|
|
|
|
|
(define ss (set (make-state '((a . #t) (b . #t)))
|
|
|
|
|
(make-state '((a . #f) (b . #t)))))
|
|
|
|
|
(define gr1 (dds-build-n-step-state-graph asyn (set s) 1))
|
|
|
|
|
(define gr-full (dds-build-state-graph asyn (set s)))
|
|
|
|
|
(define gr-full-pp (pretty-print-state-graph gr-full))
|
|
|
|
|
(define gr-full-ppb (pretty-print-boolean-state-graph gr-full))
|
|
|
|
|
(define gr-complete-bool (build-full-boolean-state-graph asyn))
|
|
|
|
|
(define gr-complete-bool-ann (build-full-boolean-state-graph-annotated asyn))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(check-equal? (dds-step-one asyn s) (set (make-state '((a . #f) (b . #f)))
|
|
|
|
|
(make-state '((a . #t) (b . #f)))))
|
|
|
|
|
(check-equal? (dds-step-one-annotated asyn s)
|
|
|
|
|
(set (cons (set 'b) '#hash((a . #t) (b . #f)))
|
|
|
|
|
(cons (set 'a) '#hash((a . #f) (b . #f)))))
|
|
|
|
|
(check-equal? (dds-step-one syn s) (set (make-state '((a . #f) (b . #f)))))
|
|
|
|
|
(check-equal? (dds-step asyn ss)
|
|
|
|
|
(set (make-state '((a . #f) (b . #t)))
|
|
|
|
|
(make-state '((a . #t) (b . #t)))))
|
|
|
|
|
(check-true (has-vertex? gr1 #hash((a . #t) (b . #f))))
|
|
|
|
|
(check-true (has-vertex? gr1 #hash((a . #f) (b . #f))))
|
|
|
|
|
(check-false (has-vertex? gr1 #hash((a . #t) (b . #t))))
|
|
|
|
|
(check-true (has-edge? gr1 #hash((a . #t) (b . #f)) #hash((a . #f) (b . #f))))
|
|
|
|
|
(check-true (has-edge? gr1 #hash((a . #t) (b . #f)) #hash((a . #t) (b . #f))))
|
|
|
|
|
(check-false (has-edge? gr1 #hash((a . #f) (b . #f)) #hash((a . #t) (b . #f))))
|
|
|
|
|
|
|
|
|
|
(check-true (has-vertex? gr-full #hash((a . #t) (b . #f))))
|
|
|
|
|
(check-true (has-vertex? gr-full #hash((a . #f) (b . #f))))
|
|
|
|
|
(check-false (has-vertex? gr-full #hash((a . #t) (b . #t))))
|
|
|
|
|
(check-true (has-edge? gr-full #hash((a . #t) (b . #f)) #hash((a . #f) (b . #f))))
|
|
|
|
|
(check-true (has-edge? gr-full #hash((a . #t) (b . #f)) #hash((a . #t) (b . #f))))
|
|
|
|
|
(check-true (has-edge? gr-full #hash((a . #f) (b . #f)) #hash((a . #t) (b . #f))))
|
|
|
|
|
(check-true (has-edge? gr-full #hash((a . #f) (b . #f)) #hash((a . #f) (b . #f))))
|
|
|
|
|
|
|
|
|
|
(check-true (has-vertex? gr-full-pp "a:#f b:#f"))
|
|
|
|
|
(check-true (has-vertex? gr-full-pp "a:#t b:#f"))
|
|
|
|
|
(check-true (has-vertex? gr-full-ppb "a:0 b:0"))
|
|
|
|
|
(check-true (has-vertex? gr-full-ppb "a:1 b:0"))
|
|
|
|
|
|
|
|
|
|
(check-true (set=?
|
|
|
|
|
(get-edges gr-complete-bool)
|
|
|
|
|
'((#hash((a . #f) (b . #f)) #hash((a . #t) (b . #f)))
|
|
|
|
|
(#hash((a . #f) (b . #f)) #hash((a . #f) (b . #f)))
|
|
|
|
|
(#hash((a . #t) (b . #f)) #hash((a . #t) (b . #f)))
|
|
|
|
|
(#hash((a . #t) (b . #f)) #hash((a . #f) (b . #f)))
|
|
|
|
|
(#hash((a . #t) (b . #t)) #hash((a . #f) (b . #t)))
|
|
|
|
|
(#hash((a . #t) (b . #t)) #hash((a . #t) (b . #t)))
|
|
|
|
|
(#hash((a . #f) (b . #t)) #hash((a . #f) (b . #t)))
|
|
|
|
|
(#hash((a . #f) (b . #t)) #hash((a . #t) (b . #t))))))
|
|
|
|
|
|
|
|
|
|
(check-true (set=?
|
|
|
|
|
(get-edges gr-complete-bool-ann)
|
|
|
|
|
'((#hash((a . #f) (b . #f)) #hash((a . #t) (b . #f)))
|
|
|
|
|
(#hash((a . #f) (b . #f)) #hash((a . #f) (b . #f)))
|
|
|
|
|
(#hash((a . #t) (b . #f)) #hash((a . #t) (b . #f)))
|
|
|
|
|
(#hash((a . #t) (b . #f)) #hash((a . #f) (b . #f)))
|
|
|
|
|
(#hash((a . #t) (b . #t)) #hash((a . #f) (b . #t)))
|
|
|
|
|
(#hash((a . #t) (b . #t)) #hash((a . #t) (b . #t)))
|
|
|
|
|
(#hash((a . #f) (b . #t)) #hash((a . #f) (b . #t)))
|
|
|
|
|
(#hash((a . #f) (b . #t)) #hash((a . #t) (b . #t))))))
|
|
|
|
|
(check-equal? (edge-weight gr-complete-bool-ann
|
|
|
|
|
#hash((a . #f) (b . #f)) #hash((a . #t) (b . #f)))
|
|
|
|
|
(set (set 'a)))
|
|
|
|
|
(check-equal? (edge-weight gr-complete-bool-ann
|
|
|
|
|
#hash((a . #f) (b . #f)) #hash((a . #f) (b . #f)))
|
|
|
|
|
(set (set 'b)))
|
|
|
|
|
(check-equal? (edge-weight gr-complete-bool-ann
|
|
|
|
|
#hash((a . #t) (b . #f)) #hash((a . #t) (b . #f)))
|
|
|
|
|
(set (set 'b)))
|
|
|
|
|
(check-equal? (edge-weight gr-complete-bool-ann
|
|
|
|
|
#hash((a . #t) (b . #f)) #hash((a . #f) (b . #f)))
|
|
|
|
|
(set (set 'a)))
|
|
|
|
|
(check-equal? (edge-weight gr-complete-bool-ann
|
|
|
|
|
#hash((a . #t) (b . #t)) #hash((a . #f) (b . #t)))
|
|
|
|
|
(set (set 'a)))
|
|
|
|
|
(check-equal? (edge-weight gr-complete-bool-ann
|
|
|
|
|
#hash((a . #t) (b . #t)) #hash((a . #t) (b . #t)))
|
|
|
|
|
(set (set 'b)))
|
|
|
|
|
(check-equal? (edge-weight gr-complete-bool-ann
|
|
|
|
|
#hash((a . #f) (b . #t)) #hash((a . #f) (b . #t)))
|
|
|
|
|
(set (set 'b)))
|
|
|
|
|
(check-equal? (edge-weight gr-complete-bool-ann
|
|
|
|
|
#hash((a . #f) (b . #t)) #hash((a . #t) (b . #t)))
|
|
|
|
|
(set (set 'a)))))
|
|
|
|
|
|
2020-03-15 16:12:35 +01:00
|
|
|
|
|
2020-03-22 14:40:23 +01:00
|
|
|
|
;;; =================================
|
|
|
|
|
;;; Tabulating functions and networks
|
|
|
|
|
;;; =================================
|
2020-03-15 16:12:35 +01:00
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
|
2020-03-22 14:34:40 +01:00
|
|
|
|
;;; Like tabulate, but supposes that the function works on states.
|
|
|
|
|
;;;
|
|
|
|
|
;;; The argument domains defines the domains of each of the component
|
|
|
|
|
;;; of the states. If headers it true, the resulting list starts with
|
|
|
|
|
;;; a listing the names of the variables of the domain and ending with
|
|
|
|
|
;;; the symbol 'f, which indicates the values of the function.
|
|
|
|
|
(define (tabulate-state func domains #:headers [headers #t])
|
2020-06-02 21:29:00 +02:00
|
|
|
|
(define tab (tabulate-state* `(,func) domains #:headers headers))
|
2020-03-22 14:34:40 +01:00
|
|
|
|
(cond
|
|
|
|
|
[headers
|
2020-06-02 21:29:00 +02:00
|
|
|
|
;; Replace 'f1 in the headers by 'f.
|
|
|
|
|
(match tab [(cons hdrs vals)
|
|
|
|
|
(cons (append (drop-right hdrs 1) '(f)) vals)])]
|
2020-03-22 14:34:40 +01:00
|
|
|
|
[else tab]))
|
|
|
|
|
|
|
|
|
|
;;; Like tabulate-state, but assumes the function is a Boolean
|
|
|
|
|
;;; function. args is a list of names of the arguments which can
|
|
|
|
|
;;; appear in the states.
|
|
|
|
|
(define (tabulate-state/boolean func args #:headers [headers #t])
|
|
|
|
|
(tabulate-state func (make-boolean-domains args) #:headers headers))
|
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "tabulate-state/boolean"
|
|
|
|
|
(define func (λ (st) (not (hash-ref st 'a))))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(check-equal? (tabulate-state/boolean func '(a)) '((a f) (#f #t) (#t #f)))))
|
|
|
|
|
|
2020-06-02 21:28:37 +02:00
|
|
|
|
;;; Like tabulate-state, but takes a list of functions over the same
|
|
|
|
|
;;; domain. If headers is #t, the first list of the result enumerates
|
|
|
|
|
;;; the variable names, and then contains a symbol 'fi for each of the
|
|
|
|
|
;;; functions, where i is replaced by the number of the function in
|
|
|
|
|
;;; the list.
|
2020-06-02 21:53:53 +02:00
|
|
|
|
(define (tabulate-state* funcs domains #:headers [headers #t])
|
2020-06-02 21:28:37 +02:00
|
|
|
|
(define tab (for/list ([st (build-all-states domains)])
|
|
|
|
|
(append (hash-map st (λ (x y) y) #t)
|
|
|
|
|
(for/list ([f funcs]) (f st)))))
|
|
|
|
|
(cond
|
|
|
|
|
[headers
|
|
|
|
|
(define var-names (hash-map domains (λ (x y) x) #t))
|
|
|
|
|
(define func-names (for/list ([_ funcs] [i (in-naturals 1)]) (string->symbol (format "f~a" i))))
|
|
|
|
|
(cons (append var-names func-names) tab)]
|
|
|
|
|
[else tab]))
|
|
|
|
|
|
|
|
|
|
;;; Like tabulate-state/boolean, but takes a list of functions.
|
2020-06-02 21:53:53 +02:00
|
|
|
|
(define (tabulate-state*/boolean funcs args #:headers [headers #t])
|
2020-06-02 21:28:37 +02:00
|
|
|
|
(tabulate-state* funcs (make-boolean-domains args) #:headers headers))
|
|
|
|
|
|
|
|
|
|
(module+ test
|
|
|
|
|
(test-case "tabulate-state*/boolean"
|
|
|
|
|
(define f1 (λ (st) (and (hash-ref st 'a) (hash-ref st 'b))))
|
|
|
|
|
(define f2 (λ (st) (or (hash-ref st 'a) (hash-ref st 'b))))
|
2020-06-02 23:33:34 +02:00
|
|
|
|
(check-equal? (tabulate-state*/boolean (list f1 f2) '(a b))
|
|
|
|
|
'((a b f1 f2)
|
|
|
|
|
(#f #f #f #f)
|
|
|
|
|
(#f #t #f #t)
|
|
|
|
|
(#t #f #f #t)
|
|
|
|
|
(#t #t #t #t)))))
|
2020-06-02 21:28:37 +02:00
|
|
|
|
|
2020-03-22 19:22:54 +01:00
|
|
|
|
;;; Tabulates a given network.
|
|
|
|
|
;;;
|
|
|
|
|
;;; For a Boolean network with n variables, returns a table with 2n
|
|
|
|
|
;;; columns and 2^n rows. The first n columns correspond to the
|
|
|
|
|
;;; different values of the variables of the networks. The last n
|
|
|
|
|
;;; columns represent the values of the n update functions of the
|
|
|
|
|
;;; network. If headers is #t, prepends a list of variable names and
|
|
|
|
|
;;; update functions (f-x, where x is the name of the corresponding
|
|
|
|
|
;;; variable) to the result.
|
|
|
|
|
(define (tabulate-network network domains #:headers [headers #t])
|
2020-06-02 23:34:19 +02:00
|
|
|
|
;; I use hash-map with try-order? set to #t to ask the hash table to
|
|
|
|
|
;; sort the keys for me.
|
2020-06-02 23:37:28 +02:00
|
|
|
|
(define-values (vars funcs) (for/lists (l1 l2)
|
2020-06-02 23:34:19 +02:00
|
|
|
|
([pair (hash-map network cons #t)])
|
|
|
|
|
(values (car pair) (cdr pair))))
|
|
|
|
|
(define tab (tabulate-state* funcs domains #:headers headers))
|
2020-03-22 19:22:54 +01:00
|
|
|
|
(cond
|
|
|
|
|
[headers
|
2020-06-02 23:34:19 +02:00
|
|
|
|
;; Replace the names of the functions tabulate-state* gave us by
|
|
|
|
|
;; what we promise in the comment.
|
|
|
|
|
(define fnames (for/list ([x (in-list vars)])
|
|
|
|
|
(string->symbol (format "f-~a" x))))
|
|
|
|
|
(match tab [(cons hdrs vals)
|
|
|
|
|
(cons (append (take hdrs (length vars)) fnames) vals)])]
|
2020-03-22 19:22:54 +01:00
|
|
|
|
[else tab]))
|
|
|
|
|
|
|
|
|
|
;;; Like tabulate-network, but assumes all the variables are Boolean.
|
|
|
|
|
(define (tabulate-boolean-network bn #:headers [headers #t])
|
|
|
|
|
(tabulate-network bn (make-boolean-domains (hash-map bn (λ (x y) x) #t))
|
|
|
|
|
#:headers headers))
|
2020-03-22 14:40:23 +01:00
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "tabulate-boolean-network"
|
|
|
|
|
(define bn (network-form->network #hash((a . (not a)) (b . b))))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(check-equal? (tabulate-boolean-network bn)
|
|
|
|
|
'((a b f-a f-b) (#f #f #t #f) (#f #t #t #t) (#t #f #f #f) (#t #t #f #t)))
|
|
|
|
|
(check-equal? (tabulate-boolean-network bn #:headers #f)
|
|
|
|
|
'((#f #f #t #f) (#f #t #t #t) (#t #f #f #f) (#t #t #f #t)))))
|
|
|
|
|
|
|
|
|
|
|
2020-03-23 22:31:58 +01:00
|
|
|
|
;;; ===================================
|
|
|
|
|
;;; Constructing functions and networks
|
|
|
|
|
;;; ===================================
|
2020-03-22 14:40:23 +01:00
|
|
|
|
|
2020-03-24 00:18:39 +01:00
|
|
|
|
;;; Given a table like the one produced by tabulate-network,
|
|
|
|
|
;;; constructs a Boolean network having this behaviour. If headers is
|
|
|
|
|
;;; #t, considers that the first element of the list are the headers
|
|
|
|
|
;;; and reads the names of the variables from them. Otherwise
|
|
|
|
|
;;; generates names for variables of the form xi, where 0 ≤ i < number
|
|
|
|
|
;;; of variables, and treats all rows in the table as defining the
|
|
|
|
|
;;; behaviour of the functions of the network. The columns defining
|
|
|
|
|
;;; the functions are taken to be in the same order as the variables
|
|
|
|
|
;;; in the first half of the function. The headers of the columns
|
|
|
|
|
;;; defining the functions are therefore discarded.
|
|
|
|
|
;;;
|
|
|
|
|
;;; This function relies on table->function, so the same caveats
|
|
|
|
|
;;; apply.
|
|
|
|
|
(define (table->network table #:headers [headers #t])
|
|
|
|
|
(define n (/ (length (car table)) 2))
|
|
|
|
|
;; Get the variable names from the table or generate them, if
|
|
|
|
|
;; necessary.
|
|
|
|
|
(define var-names (cond [headers (take (car table) n)]
|
|
|
|
|
[else (for ([i (in-range n)])
|
|
|
|
|
(symbol->string (format "x~a" i)))]))
|
|
|
|
|
;; Drop the headers if they are present.
|
|
|
|
|
(define tab (cond [headers (cdr table)]
|
|
|
|
|
[else table]))
|
|
|
|
|
;; Split the table into the inputs and the outputs of the functions.
|
|
|
|
|
(define-values (ins outs) (multi-split-at tab n))
|
|
|
|
|
;; Transpose outs to have functions define by lines instead of by
|
|
|
|
|
;; columns.
|
|
|
|
|
(define func-lines (lists-transpose outs))
|
|
|
|
|
;; Make states out of inputs.
|
|
|
|
|
(define st-ins (for/list ([in ins]) (make-state (map cons var-names in))))
|
|
|
|
|
;; Construct the functions.
|
|
|
|
|
(define funcs (for/list ([out func-lines])
|
|
|
|
|
(table->function (for/list ([in st-ins] [o out])
|
|
|
|
|
(list in o)))))
|
|
|
|
|
;; Construct the network.
|
|
|
|
|
(make-network-from-functions (map cons var-names funcs)))
|
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "table->network"
|
|
|
|
|
(define n (table->network '((x1 x2 f1 f2)
|
|
|
|
|
(#f #f #f #f)
|
|
|
|
|
(#f #t #f #t)
|
|
|
|
|
(#t #f #t #f)
|
|
|
|
|
(#t #t #t #t))))
|
|
|
|
|
(define f1 (hash-ref n 'x1))
|
|
|
|
|
(define f2 (hash-ref n 'x2))
|
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(check-false (f1 (make-state '((x1 . #f) (x2 . #f)))))
|
|
|
|
|
(check-false (f1 (make-state '((x1 . #f) (x2 . #t)))))
|
|
|
|
|
(check-true (f1 (make-state '((x1 . #t) (x2 . #f)))))
|
|
|
|
|
(check-true (f1 (make-state '((x1 . #t) (x2 . #t)))))
|
|
|
|
|
|
|
|
|
|
(check-false (f2 (make-state '((x1 . #f) (x2 . #f)))))
|
|
|
|
|
(check-true (f2 (make-state '((x1 . #f) (x2 . #t)))))
|
|
|
|
|
(check-false (f2 (make-state '((x1 . #t) (x2 . #f)))))
|
|
|
|
|
(check-true (f2 (make-state '((x1 . #t) (x2 . #t)))))))
|
|
|
|
|
|
2020-03-20 22:22:33 +01:00
|
|
|
|
|
2020-03-22 14:40:23 +01:00
|
|
|
|
;;; =============================
|
|
|
|
|
;;; Random functions and networks
|
|
|
|
|
;;; =============================
|
2020-03-20 22:22:33 +01:00
|
|
|
|
|
2020-03-22 14:35:26 +01:00
|
|
|
|
;;; Generates a random function accepting a state over the domains
|
|
|
|
|
;;; given by arg-domains and producing values in func-domain.
|
|
|
|
|
(define (random-function/state arg-domains func-domain)
|
|
|
|
|
(table->function (for/list ([st (build-all-states arg-domains)])
|
|
|
|
|
(list st (random-ref func-domain)))))
|
|
|
|
|
|
|
|
|
|
;;; Like random-function/state, but the domains of the arguments and
|
|
|
|
|
;;; of the function are Boolean. args is a list of names of the
|
|
|
|
|
;;; variables appearing in the state.
|
|
|
|
|
(define (random-boolean-function/state args)
|
|
|
|
|
(random-function/state (make-boolean-domains args) '(#f #t)))
|
2020-03-22 18:40:50 +01:00
|
|
|
|
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(module+ test
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(test-case "random-boolean-function/state"
|
|
|
|
|
(random-seed 0)
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(define f (random-boolean-function/state '(x1 x2)))
|
|
|
|
|
(check-equal? (tabulate-state/boolean f '(x1 x2))
|
2020-05-27 23:39:38 +02:00
|
|
|
|
'((x1 x2 f) (#f #f #f) (#f #t #f) (#t #f #t) (#t #t #t)))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(check-equal? (tabulate-state/boolean f '(x1 x2) #:headers #f)
|
2020-05-27 23:39:38 +02:00
|
|
|
|
'((#f #f #f) (#f #t #f) (#t #f #t) (#t #t #t)))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
(define bn (random-boolean-network/vars 3))
|
|
|
|
|
(check-equal? (tabulate-boolean-network bn)
|
|
|
|
|
'((x0 x1 x2 f-x0 f-x1 f-x2)
|
2020-05-27 23:39:38 +02:00
|
|
|
|
(#f #f #f #f #t #f)
|
|
|
|
|
(#f #f #t #t #f #f)
|
|
|
|
|
(#f #t #f #f #t #t)
|
|
|
|
|
(#f #t #t #t #f #f)
|
|
|
|
|
(#t #f #f #t #f #t)
|
|
|
|
|
(#t #f #t #f #f #t)
|
|
|
|
|
(#t #t #f #f #f #f)
|
|
|
|
|
(#t #t #t #t #t #t)))))
|
2020-05-22 23:40:40 +02:00
|
|
|
|
|
2020-03-22 18:40:50 +01:00
|
|
|
|
;;; Generates a random network from the given domain mapping.
|
2020-03-22 19:28:44 +01:00
|
|
|
|
(define (random-network domains)
|
2020-03-22 18:40:50 +01:00
|
|
|
|
(for/hash ([(x x-dom) (in-hash domains)])
|
|
|
|
|
(values x (random-function/state domains x-dom))))
|
|
|
|
|
|
|
|
|
|
;;; Generates a random Boolean network with the given variables.
|
2020-03-22 19:28:44 +01:00
|
|
|
|
(define (random-boolean-network vars)
|
2020-03-22 18:40:50 +01:00
|
|
|
|
(random-network (make-boolean-domains vars)))
|
|
|
|
|
|
|
|
|
|
;;; Like random-boolean-network, but also generates the names of the
|
|
|
|
|
;;; variables for the network. The variables have the names x0 to xk,
|
|
|
|
|
;;; where k = n - 1.
|
2020-03-22 19:28:44 +01:00
|
|
|
|
(define (random-boolean-network/vars n)
|
2020-03-22 18:40:50 +01:00
|
|
|
|
(random-boolean-network (for/list ([i (in-range n)]) (string->symbol (format "x~a" i)))))
|
2020-07-21 00:13:56 +02:00
|
|
|
|
|
|
|
|
|
|
|
|
|
|
;;; ===================
|
|
|
|
|
;;; TBF/TBN and SBF/SBN
|
|
|
|
|
;;; ===================
|
|
|
|
|
|
2020-07-22 23:46:58 +02:00
|
|
|
|
;;; Applies a TBF to a state.
|
|
|
|
|
;;;
|
|
|
|
|
;;; The values of the variables of the state are ordered by hash-map
|
|
|
|
|
;;; and fed to the TBF in order. The number of the inputs of the TBF
|
|
|
|
|
;;; must match the number of variables in the state.
|
2020-07-22 23:53:20 +02:00
|
|
|
|
(define (apply-tbf-to-state tbf st)
|
2020-07-22 23:46:58 +02:00
|
|
|
|
(apply-tbf tbf (list->vector (hash-map st (λ (_ val) val)))))
|
|
|
|
|
|
|
|
|
|
(module+ test
|
2020-07-23 00:22:39 +02:00
|
|
|
|
(test-case "apply-tbf-to-state"
|
|
|
|
|
(define st (make-state '((x1 . 0) (x2 . 1))))
|
|
|
|
|
(define f (tbf #(1 1) 1))
|
|
|
|
|
(check-equal? (apply-tbf-to-state f st) 0)))
|
2020-07-23 00:06:26 +02:00
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;;; A state TBF is a TBF with named inputs. A state TBF can be
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;;; applied to states in an unambiguous ways.
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2020-07-23 00:17:17 +02:00
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(struct tbf/state (weights threshold) #:transparent)
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2020-07-23 00:06:26 +02:00
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;;; Shortcuts for acessing fields of a state/tbf.
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2020-07-23 00:11:14 +02:00
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(define tbf/state-w tbf/state-weights)
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(define tbf/state-θ tbf/state-threshold)
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2020-07-23 00:06:26 +02:00
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2020-07-23 00:19:25 +02:00
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;;; Makes a state/tbf from a list of pairs of names of variables and
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;;; weights, as well as a threshold.
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(define (make-tbf/state pairs threshold)
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(tbf/state (make-immutable-hash pairs) threshold))
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2020-07-23 00:20:00 +02:00
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(module+ test
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(test-case "tbf/state"
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(define f (make-tbf/state '((x1 . 1) (x2 . 1)) 1))
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(check-equal? (tbf/state-w f) #hash((x1 . 1) (x2 . 1)))
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(check-equal? (tbf/state-θ f) 1)))
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2020-08-01 23:24:51 +02:00
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;;; Applies a state TBF to its inputs.
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;;;
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;;; Applying a TBF consists in multiplying the weights by the
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;;; corresponding inputs and comparing the sum of the products to the
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;;; threshold.
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;;;
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;;; This function is similar to apply-tbf, but applies a state TBF (a
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;;; TBF with explicitly named inputs) to a state whose values are 0
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;;; and 1.
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(define (apply-tbf/state tbf st)
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(any->01 (> (foldl + 0 (hash-values
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(hash-intersect (tbf/state-w tbf)
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st
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#:combine *)))
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(tbf/state-θ tbf))))
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(module+ test
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(test-case "apply-tbf/state"
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(define st1 (make-state '((a . 1) (b . 0) (c . 1))))
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(define st2 (make-state '((a . 1) (b . 1) (c . 0))))
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(define tbf (make-tbf/state '((a . 2) (b . -2)) 1))
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(check-equal? (apply-tbf/state tbf st1) 1)
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(check-equal? (apply-tbf/state tbf st2) 0)))
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2020-10-10 23:23:43 +02:00
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;;; Reads a list of tbf/state from a list of list of numbers.
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;;;
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;;; The last element of each list is taken to be the threshold of the
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;;; TBFs, and the rest of the elements are taken to be the weights.
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;;;
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;;; If headers is #t, the names of the variables to appear as the
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;;; inputs of the TBF are taken from the first list. The last element
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;;; of this list is discarded.
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;;;
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;;; If headers is #f, the names of the variables are generated as xi,
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;;; where i is the index of the variable.
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(define (lists->tbfs/state lsts #:headers [headers #t])
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(define-values (var-names rows)
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(if headers
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(values (car lsts) (cdr lsts))
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(values (for/list ([i (in-range (length (car lsts)))])
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(string->symbol (format "x~a" i)))
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lsts)))
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(for/list ([lst (in-list rows)])
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(define-values (ws θ) (split-at-right lst 1))
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(make-tbf/state (for/list ([x (in-list var-names)]
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[w (in-list ws)])
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(cons x w))
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(car θ))))
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(module+ test
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(test-case "lists->tbfs/state"
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(define tbfs '((1 2 3) (1 1 2)))
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(check-equal? (lists->tbfs/state tbfs #:headers #f)
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(list
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(tbf/state '#hash((x0 . 1) (x1 . 2)) 3)
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(tbf/state '#hash((x0 . 1) (x1 . 1)) 2)))
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(check-equal? (lists->tbfs/state (cons '(a b f) tbfs))
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(list
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(tbf/state '#hash((a . 1) (b . 2)) 3)
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(tbf/state '#hash((a . 1) (b . 1)) 2)))))
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2020-07-23 00:06:26 +02:00
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;;; A TBN is a network form mapping TBFs to variables.
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(define tbn? (hash/c variable? tbf?))
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