#lang racket ;;; dds/networks ;;; This module provides some quick definitions for and analysing ;;; network models. A network is a set of variables which are updated ;;; according to their corresponding update functions. The variables ;;; to be updated at each step are given by the mode. ;;; ;;; This model can generalise Boolean networks, TBANs, multivalued ;;; networks, etc. (require "utils.rkt" graph) (provide ;; Functions (contract-out [update (-> network? state? (listof variable?) state?)] [make-state (-> (listof (cons/c symbol? any/c)) state?)] [make-network-from-functions (-> (listof (cons/c symbol? update-function/c)) network?)] [update-function-form->update-function (-> update-function-form? update-function/c)] [network-form->network (-> network-form? network?)] [make-network-from-forms (-> (listof (cons/c symbol? update-function-form?)) network?)] [list-interactions (-> network-form? variable? (listof variable?))] [build-interaction-graph (-> network-form? graph?)] [build-all-states (-> (listof (cons/c variable? generic-set?)) (listof state?))]) ;; Predicates (contract-out [variable? (-> any/c boolean?)] [state? (-> any/c boolean?)] [update-function-form? (-> any/c boolean?)] [network-form? (-> any/c boolean?)]) ;; Contracts (contract-out [state/c contract?] [network/c contract?] [update-function/c contract?]) ;; Syntax st nn) ;;; ================= ;;; Basic definitions ;;; ================= (define variable? symbol?) ;;; A state of a network is a mapping from the variables of the ;;; network to their values. (define state? variable-mapping?) (define state/c (flat-named-contract 'state state?)) ;;; An update function is a function computing a value from the given ;;; state. (define update-function/c (-> state? any/c)) ;;; A network is a mapping from its variables to its update functions. (define network? variable-mapping?) (define network/c (flat-named-contract 'network network?)) ;;; Given a state s updates all the variables from xs. This ;;; corresponds to a parallel mode. (define (update bn ; the Boolean network s ; the state to operate on xs) ; the variables to update (let ([new-s (hash-copy s)]) (for ([x xs]) (let ([f (hash-ref bn x)]) (hash-set! new-s x (f s)))) new-s)) ;;; A version of make-hash restricted to creating network states (see ;;; contract). (define (make-state mappings) (make-hash mappings)) ;;; A shortcut for make-state. (define-syntax-rule (st mappings) (make-state mappings)) ;;; A version of make-hash restricted to creating networks. (define (make-network-from-functions funcs) (make-hash funcs)) ;;; ================================= ;;; Syntactic description of networks ;;; ================================= ;;; An update function form is any form which can appear as a body of ;;; a function and which can be evaluated with eval. For example, ;;; '(and x y (not z)) or '(+ 1 a (- b 10)). (define update-function-form? any/c) ;;; A Boolean network form is a mapping from its variables to the ;;; forms of their update functions. (define network-form? variable-mapping?) ;;; Build an update function from an update function form. (define (update-function-form->update-function form) (λ (s) (eval-with s form))) ;;; Build a network from a network form. (define (network-form->network bnf) (make-hash (hash-map bnf (λ (x form) (cons x (update-function-form->update-function form)))))) ;;; Build a network from a list of pairs of forms of update functions. (define (make-network-from-forms forms) (network-form->network (make-hash forms))) ;;; A shortcut for make-network-from-forms. (define-syntax-rule (nn forms) (make-network-from-forms forms)) ;;; ============================ ;;; Inferring interaction graphs ;;; ============================ ;;; I allow any syntactic forms in definitions of Boolean functions. ;;; I can still find out which Boolean variables appear in those ;;; syntactic form, but I have no reliable syntactic means of finding ;;; out what kind of action do they have (inhibition or activation) ;;; since I cannot do Boolean minimisation (e.g., I cannot rely on not ;;; appearing before a variable, since (not (not a)) is equivalent ;;; to a). On the other hand, going through all Boolean states is ;;; quite resource-consuming and thus not always useful. ;;; ;;; In this section I provide inference of both unsigned and signed ;;; interaction graphs, but since the inference of signed interaction ;;; graphs is based on analysing the dynamics of the networks, it may ;;; be quite resource-consuming. ;;; Lists the variables of the network form appearing in the update ;;; function form for x. (define (list-interactions nf x) (set-intersect (extract-symbols (hash-ref nf x)) (hash-keys nf))) ;;; Builds the graph in which the vertices are the variables of a ;;; given network, and which contains an arrow from a to b whenever a ;;; appears in (list-interactions a). (define (build-interaction-graph n) (transpose (unweighted-graph/adj (hash-map n (λ (var _) (cons var (list-interactions n var))))))) ;;; Given a list of pairs mapping variables to generic sets of their ;;; possible values, constructs the list of all possible states. (define (build-all-states vars-domains) (let ([vars (map car vars-domains)] [domains (map cdr vars-domains)]) (for/list ([s (apply cartesian-product domains)]) (make-state (for/list ([var vars] [val s]) (cons var val))))))