diff --git a/modules/programs/neomutt.nix b/modules/programs/neomutt.nix
index 1067bda1..d338a580 100644
--- a/modules/programs/neomutt.nix
+++ b/modules/programs/neomutt.nix
@@ -296,7 +296,12 @@ let
           pkgs.writeText "signature.txt" account.signature.text
         }";
     in ''
-      # Generated by Home Manager.
+      # Generated by Home Manager.${
+        optionalString cfg.unmailboxes ''
+
+          unmailboxes *
+        ''
+      }
       set ssl_force_tls = ${
         lib.hm.booleans.yesNo (imap.tls.enable || imap.tls.useStartTls)
       }
@@ -397,6 +402,17 @@ in {
           default = true;
         };
 
+      unmailboxes = mkOption {
+        type = types.bool;
+        default = false;
+        description = ''
+          Set `unmailboxes *` at the start of account configurations.
+          It removes previous sidebar mailboxes when sourcing an account configuration.
+
+          See <http://www.mutt.org/doc/manual/#mailboxes> for more information.
+        '';
+      };
+
       extraConfig = mkOption {
         type = types.lines;
         default = "";
diff --git a/tests/modules/programs/neomutt/default.nix b/tests/modules/programs/neomutt/default.nix
index d13b870e..5666ade0 100644
--- a/tests/modules/programs/neomutt/default.nix
+++ b/tests/modules/programs/neomutt/default.nix
@@ -14,4 +14,5 @@
   neomutt-with-signature = ./neomutt-with-signature.nix;
   neomutt-with-signature-command = ./neomutt-with-signature-command.nix;
   neomutt-with-starttls = ./neomutt-with-starttls.nix;
+  neomutt-unmailboxes = ./neomutt-unmailboxes.nix;
 }
diff --git a/tests/modules/programs/neomutt/hm-example.com-unmailboxes-expected.conf b/tests/modules/programs/neomutt/hm-example.com-unmailboxes-expected.conf
new file mode 100644
index 00000000..35822cee
--- /dev/null
+++ b/tests/modules/programs/neomutt/hm-example.com-unmailboxes-expected.conf
@@ -0,0 +1,34 @@
+# Generated by Home Manager.
+unmailboxes *
+
+set ssl_force_tls = yes
+set certificate_file=/etc/ssl/certs/ca-certificates.crt
+
+# GPG section
+set crypt_autosign = no
+set crypt_opportunistic_encrypt = no
+set pgp_use_gpg_agent = yes
+set mbox_type = Maildir
+set sort = "threads"
+
+# MTA section
+set sendmail='msmtpq --read-envelope-from --read-recipients'
+
+
+
+
+
+# MRA section
+set folder='/home/hm-user/Mail/hm@example.com'
+set from='hm@example.com'
+set postponed='+Drafts'
+set realname='H. M. Test'
+set record='+Sent'
+set spoolfile='+Inbox'
+set trash='+Trash'
+
+
+# Extra configuration
+
+
+unset signature
diff --git a/tests/modules/programs/neomutt/neomutt-unmailboxes.nix b/tests/modules/programs/neomutt/neomutt-unmailboxes.nix
new file mode 100644
index 00000000..162379b8
--- /dev/null
+++ b/tests/modules/programs/neomutt/neomutt-unmailboxes.nix
@@ -0,0 +1,30 @@
+{ config, lib, pkgs, ... }:
+
+with lib;
+
+{
+  imports = [ ../../accounts/email-test-accounts.nix ];
+
+  config = {
+    accounts.email.accounts = {
+      "hm@example.com" = {
+        msmtp.enable = true;
+        neomutt.enable = true;
+        imap.port = 993;
+      };
+    };
+
+    programs.neomutt.enable = true;
+    programs.neomutt.unmailboxes = true;
+
+    test.stubs.neomutt = { };
+
+    nmt.script = ''
+      assertFileExists home-files/.config/neomutt/hm@example.com
+      assertFileContent home-files/.config/neomutt/hm@example.com ${
+        ./hm-example.com-unmailboxes-expected.conf
+      }
+    '';
+  };
+}
+